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KMID : 0361720070180040378
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Korean Journal of perinatology
2007 Volume.18 No. 4 p.378 ~ p.384
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Obstetrical outcomes of idopathic thrombocytopenic purpura in pregnancy
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Song Song-Ah
Shin Seung-Ju
Choi Young-Il
Kim Su-Hyen
Shin Ji-Eun
Oh Yei-Eun
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Abstract
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Objective : This study might help to make a clinical guidelines for obstetrical ITP patients and their infants.
Methods : We studied 19 cases of deliveries and 22 neonatal cases which were under the diagnosis of maternal ITP, reviewing medical charts from march, 1998 to march, 2007 retrospectively.
Results : Corticosteroid treatment was administrated in 13 cases, high-dose immunoglobulin therapy in 3 cases, and concentrated platelet transfusion in 17 cases as their antenatal care. Ten (45%) vaginal delivery and twelve (55%) cesarean section were performed. There were no obstetrical complications associated with their ITP and only four infants with platelet counts below the 150,000/㎕ were reported after birth. However there were not any signs and symptoms of neonatal complications resulted from their maternal ITP.
Conclusion : Our results demonstrate that mothers with ITP can successfully deliver healthy infants in most case. Although maternal and fetal bleeding may occur, such a fatal complication is uncommon.
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KEYWORD
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ITP, pregnancy, delivery, platelet
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